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Protein S -thiolations protect the thiol groups against the irreversible overoxidation to Cys sulfinic (R-SO 2 H) and sulfonic acid (R-SO 3 H)

However, a recent phase II clinical trial evaluating the efficacy of selonsertib combined with prednisolone in the treatment of SAH patients showed no improvement in liver function or mortality compared with prednisolone alone (Mathurin et al., 2018)

Kong L, Du W, Cui Z, Wang L, Yang Z, Zhang H, Lin D (2016) Expression of lactate dehydrogenase C in MDA-MB-231 cells and its role in tumor invasion and migration

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doi:10.1186/1471-2377-11-139 Tirouvanziam R, Obukhanych TV, Laval J, Aronov PA, Libove R, Banerjee AG, Parker KJ, O'Hara R, Herzenberg LA, Herzenberg LA, Hardan AY: Distinct plasma profile of polar neutral amino acids, leucine and glutamate in children with autism spectrum disorders